Publication

Journal Paper / Conferee Paper / Oral Presentation

A.    Journal Paper (2008- to now)

1.  Chih-Chuang Liaw, Yu-Liang Yang, Mei Chen, Fang-Rong Chang, Su-Li Chen, Shih-Hsiung Wu, Yang-Chang Wu, ‘Mono-Tetrahydrofuran Annonaceous Acetogenins from Annona squamosa as Cytotoxic Agents and Calcium Ion Chelators’, J. Nat. Prod. 2008, 71, 764-771. (Impact factor 2.551, applied chem 7/62)

2.  Chia-Hua Liang, Guey-Horng Wang, Chih-Chuang Liaw, Mei-Feng Lee, Shih-Hao Wang, Da-Long Cheng and Tzung-Han Chou, ‘Extracts from Cladiella australis, Clavularia viridis and Klyxum simplex (Soft Corals) are Capable of Inhibiting the Growth of Human Oral Squamous Cell Carcinoma Cells’, Mar. Drugs 2008, 6, 595-606. (Impact factor 1.103, Medicinal Chemistry, 29/41)

3.  Yi-Chien Lin, Yaun-Chao Huang, Sheng-Chih Chen, Chih-Chuang Liaw, Sheng-Chu Kuo, Li-Jiau Huang, Po-Wu Gean, ‘Neuroprotective Effects of Ugonin K on Hydrogen Peroxide-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells’, Neurochem. Res., 2009, 34, 923-930. (Impact factor 1.811, Neurosciences, 142/211)

4.  Yaun-Chao Huang, Tsong-Long Hwang, Chih-Shiang Chang, Yu-Liang Yang, Chia-Ning Shen, Wen-Ying Liao, Sheng-Chih Chen, and Chih-Chuang Liaw*, ‘Anti-inflammatory Flavonoids from the Rhizomes of Helminthostachys zeylanica’, J. Nat. Prod. 2009, 72, 1273-1278. (Impact factor 2.843, SCI, * correspondence)

5.  Chia-Lin Lee, Lien-Chai Chiang, Li-Hung Cheng, Chih-Chuang Liaw, Mohamed H. Abd El-Razek, Fang-Rong Chang, and Yang-Chang Wu, ‘Influenza A (H1N1) Antiviral and Cytotoxic Agents from Ferula assa-foetida’, J. Nat. Prod. 2009, 72, 1568-1572. (SCI)

6.  Yu-Liang Yang, Wen-Ying Liao, Wan-Yun Liu, Chih-Chuang Liaw, Chia-Ning Shen, Zih-You Huang, and Shih-Hsiung Wu, ‘Discovery of New Natural Products by Intact-cell Mass Spectrometry and LC-SPE-NMR--Malbranpyrroles, Novel Polyketides from Thermophilic Fungus Malbranchea sulfurea’, Chem. Eur. J. 2009, 15, 11573-11580. (IF 5.454, Chemistry, Multidisciplinary, 12/125)

7. Yaun-Chao Huang, Tsong-Long Hwang, Yu-Liang Yang, Shih-Hsiung Wu, Mei-Hua Hsu, Jih-Pyang Wang, Sheng-Chih Chen, Li-Jiau Huang, and Chih-Chuang Liaw*, ‘Acetogenin and Prenylated Flavonoids from Helminthostachys zeylanica with Inhibitory Activity on Superoxide Generation and Elastase Release by Neutrophils’, Planta Med.,  2010, 76, 447-453. (Impact factor 2.369, * correspondence)

8. Chih-Chuang Liaw, Tung-Ying Wu, Fang-Rong Chang, Yang-Chang Wu, ‘Historic Perspectives of Annonaceous Acetogenins. From Chemical Bench to Preclinical Trials’, Planta Med., 2010, 76, 1390-1404. (Impact factor 2.369)

9. Chih-Chuang Liaw,* Wen-Ying Liao, Chien-Sheng Chen, Yang-Chang Wu, Shu-Chuan Jao, Chia-Ning Shen*, and Shih-Hsiung Wu,* “Calcium-chelating Capability of Tetrahydrofuranic Moieties Modulates Cytotoxicity of Annonaceous Acetogenins” Angew. Chem. Int. Ed. 2011, 50, 7885–7891. (Impact factor 12.730, Chemistry, Multidisciplinary, 5/140, * correspondence)

10. Chih-Chuang Liaw, Jia-Lin Chang,* Shou-Fong Chen, Jhih-Hong Huang, Jyun-Fu Sie, Yung-Yi Cheng, “Simulations of circular dichroism spectra of a pair of diterpene enantiomers by time-dependent density functional theory” Chem. Phys. Lett. 2011, 517, 51-54. (Impact factor 2.230, Chemistry)

11. Wen-Ying Liao, Chia-Ning Shen, Li-Hua Lin, Yu-Liang Yang, Hsin-Ying Han, Jing-Wei Chen, Sheng-Chu Kuo, Shih-Hsiung Wu, and Chih-Chuang Liaw*, “Asperjinone, A Nor-Neolignan, and Terrein, A Suppressor of ABCG2-expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus.” J. Nat. Prod. 2012, 75, 630-635. (IF: 3.112,  27/190=14.2%, Plant Sciences, * correspondence)

12. David J. Gonzalez, Yuquan Xu, Yu-Liang Yang, Eduardo Esquenazi, Wei-Ting Liu, Anna Edlund, Tram Duong, Liangcheng Du, István Molnár, William H. Gerwick, Paul R. Jensen, Michael Fischbach, Chih-Chuang Liaw, Paul Straight, Victor Nizet, Pieter C. Dorrestein, "Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes", J. Prot. 2012, 75, 5069-5076. (IF: 4.878, Biochemical Research Methods, 12/72=16.7%).

13. Shwu-Li Wu, Jui-Hsin Su, Chiung-Yao Huang, Chi-Jen Tai, Ping-Jyun Sung, Chih-Chung Liaw and Jyh-Horng Sheu, "Simplexins P–S, Eunicellin-Based Diterpenes from the Soft Coral Klyxum simplex", Mar. Drugs 2012, 10, 1203-1211. (IF: 3.854, Chemistry, Medicinal, 7/59=11.9%).

14. Hui-Yu Fang,# Chih-Chuang Liaw,# Chih-Hua Chao, Zhi-Hong Wen, Yang-Chang Wu, Chi-Hsin Hsu, Chang-Feng Dai, and Jyh-Horng Sheu, “Bioactive Pregnane–type Steroids from the Soft Coral Scleronephthya gracillimum”, Tetrahedron 2012, 68, 9694-9700. (IF: 3.025, Chemistry, Organic, 16/56=28.6%, #equal contribution).

15. Hui-Chi Huang, Chih-Chuang Liaw, Hsin-Ling Yang, You-Cheng Hseu, Hsiou-Ting Kuo, Yao-Ching Tsai, Shih-Chang Chien, Sakae Amagaya, Yu-Chang Chen, Yueh-Hsiung Kuo. “Lanostane triterpenoids and sterols from Antrodia camphorate.” Phytochemistry 2012, 84, 177–183. (IF: 3.351, Plant Sciences, 22/190=11.6%)

16. Yung-Yi Cheng, Jai-Sing Yang, Shih-Chang Tsai, Chih-Chuang Liaw, Jing-Gung Chung, Li-Jiau Huang, Kuo-Hsiung Lee, Chi-Cheng Lu, Hsi-Cheng Chien, Minoru Tsuzuki, Sheng-Chu Kuo, “The newly synthesized 2-(3-hydroxy-5-methoxyphenyl)-6,7-methylenedioxyquinolin-4-one triggers cell apoptosis through induction of oxidative stress and upregulation of the p38 MAPK signaling pathway in HL-60 human leukemia cells.” Oncology Reports. 2012, 28, 1482-1490. (IF: 1.84, Oncology, 131/196=66.8%)

17. Shu-Jing Wu, Chih-Chuang Liaw, Shin-Zon Pan, Hsing-Chia Yang, Lean-Teik Ng, “Phellinus linteus polysaccharides and their immunomodulatory properties in human monocytic cells”, J. Funct. Foods, 2013, 5, 679–688 (IF: 3.574, Food Science & Technology, 7/123=5.7%).

18. Chun-Chi Chen, Yung-Lin Yang, Chun-Lin Ou, Chih-Hung Chou, Chih-Chuang Liaw, Po-Chiao Lin.* “Direct monitoring of chemical transformations by combining thin layer chromatography with nanoparticle-assisted laser desorption/ionization mass spectrometry”, Analyst, 2013, 138, 1379–1385 (IF=4.107, Chemistry, Analytical, 7/74=9.5%)

19. Wen-Ying Liao,# Chih-Chuang Liaw,# Yua-Chia Huang, Hsin-Ying Han, Hung-Wei Hsu, Shiaw Min Hwang, Sheng-Chu Kuo and Chia-Ning Shen*. "Cyclohexylmethyl flavonoids suppress propagation of breast cancer stem cells via downregulation of NANOG", Evid. Based Complement. Alternat. Med. 2013, 2013, Article ID 170261, 14 pages (IF: 1.880, Integrative & Complementary Medicine, 7/24=29.2%, # equal contribution).

20. Chih-Chuang Liaw, Yu-Chang Chen, Guan-Jhong Huang, Yao-Ching Tsai, Shih-Chang Chien, Jyh-Horng Wu, Sheng-Yang Wang, Louis Kuoping Chao, Ping-Jyun Sung, Hui-Chi Huang, Yueh-Hsiung Kuo. “Anti-inflammatory Lanostanoids and Lactone Derivatives from Antrodia camphorate.” J. Nat. Prod. 2013, 76, 489−494. (IF: 3.789, Plant Sciences, 23/200=11.5%)

21. Jen-Yang Tang, Jin-Ching Lee, Yung-Ting Chang, Ming-Feng Hou, Hurng-Wern Huang, Chih-Chuang Liaw,* and Hsueh-Wei Chang.* “Long Noncoding RNAs-Related Diseases, Cancers, and Drugs.” Sci. World J. 2013, 2013, Article ID 943539, 7 pages, http://dx.doi.org/10.1155/2013/943539. (IF: 1.219, Multidisciplinary Sciences, 16/55=29.1%)

22. Hui-Chi Huang, Guan-Jhong Huang, Chih-Chuang Liaw, Chang-Syun Yang, Chung-Ping Yang, Chao-Lin Kuo, Yen-Hsueh Tseng, Sheng-Yang Wang, Wen-Te Chang, Yueh-Hsiung Kuo, A new megastigmane from Kalanchoe tubiflora (Harvey) Hamet, Phytochem. Lett. 2013, 6, 379-382 (IF: 1.450, Plant Sciences, 97/200=48.5%)

23. Hui-Chi Huang, Ming-Kuem Lin, Hsin-Ling Yang, You-Cheng Hseu, Chih-Chuang Liaw, Yen-Hsueh Tseng, Minoru Tsuzuki, Yueh-Hsiung Kuo. Cardenolides and Bufadienolide Glycosides from Kalanchoe tubiflora and Evaluation of Cytotoxicity, Planta Med. 2013, 79, 1362-1369. (IF: 2.152, Plant Sciences, 60/200=30.0%)

24. Chiung-Yao Huang, Chih-Chuang Liaw, Bo-Wei Chen, Pei-Chin Chen, Jui-Hsin Su, Ping-Jyun Sung, Chang-Feng Dai, Michael Y. Chiang, and Jyh-Horng Sheu,* “Withanolide-Based Steroids from the Cultured Soft Coral Sinularia brassica.” J. Nat. Prod. 2013, 76, 1902-1908. (IF: 3.789, Plant Sciences, 23/200=11.5%)

25. Chao-Jen Shih,# Pi-Yu Chen,# Chih-Chuang Liaw,# Ying-Mi Lai, Yu-Liang Yang, Bringing microbial interactions to light using imaging mass spectrometry, Nat. Prod. Rep. 2014, 31, 739-755. (# equal contribution) (IF: 10.107, Chemistry, Medicinal, 1/59=1.7%)

26. Tung-Ho Wu,# Yung-Yi Cheng,# Chao-Jung Chen, Lean-Teik Ng, Li-Chen Chou, Li-Jiau Huang, Yung-Husan Chen, Sheng-Chu Kuo, Mohamed El-Shazly, Yang-Chang Wu, Fang-Rong Chang,* and Chih-Chuang Liaw,* “Three New Clerodane Diterpenes from Polyalthia longifolia var. pendula”, Molecules 2014, 19, 2049-2060. (IF: 2.416, Chemistry, Organic, 21/57=36.8%)

27. Chun-Yu Chen,# Chih-Chuang Liaw,# Yi-Hsuan Chen, Wen-Yi Chang, Pei-Jen Chung, Tsong-Long Hwang, “A novel immunomodulatory effect of ugonin U in human neutrophils via stimulation of phospholipase C” Free Radic. Biol. Med. 2014, 72, 222-231. (# equal contribution) (IF: 5.736, Endocrinology & Metabolism, 16/128=12.5%)

28. Tung-Ho Wu,# Yung-Yi Cheng,# Jing-Ru Liou,# Tzong-Der Way, Chao-Jung Chen, Yung-Husan Chen, Sheng-Chu Kuo, Mohamed El-Shazly, Fang-Rong Chang, Yang-Chang Wu,* and Chih-Chuang Liaw,* “Clerodane diterpenes from Polyalthia longifolia var. pendula protect SK-N-MC human neuroblastoma cells from β-Amyloid insult”, RSC Adv. 2014, 4, 23707-23712 (IF: 3.840, Chemistry, Multidisciplinary, 33/157=21.0%)

29. Hui-Yu Fang, Shu-Fen Chiou, Chokkalingam Uvarani, Zih-Hong Wen, Chi-Hsin Hsu, Yang-Chang Wu, Wei-Lung Wang, Chih-Chuang Liaw,* and Jyh-Horng Sheu,* “Cytotoxic, anti-inflammatory and antibacterial sulfur-containing polybromoindoles from the Formosan red alga Laurencia brongniartii”, Bull. Chem. Soc. Jpn. 2014 87, 1278–1280. (IF: 2.210, Chemistry, Multidisciplinary, 57/157=36.3%)

30. Chih-Chuang Liaw,* Yu-Liang Yang, Chun-Kuang Lin, Jin-Ching Lee, Wen-Ying Liao, Chia-Ning Shen, Jyh-Horng Sheu, and Shih-Hsiung Wu,* “New Meroterpenoids from Aspergillus terreus with Inhibition of Cyclooxygenase-2 Expression”, Org. Lett. 2015, 17, 2330–2333. (IF: 6.364, Chemistry, Organic, 4/57=7.0%)

31. Chun-Kuang Lin, Chin-Kai Tseng, Kai-Hsun Chen, Shih-Hsiung Wu, Chih-Chuang Liaw,* Jin-Ching Lee,* “Betulinic acid exerts anti-hepatitis C virus activity via the suppression of NF-κB and MAPK-ERK1/2-mediated cyclooxygenase-2 expression”, Br. J. Pharmacol. 2015, 172, 4481-4492. (IF: 4.842, Pharmacology & Pharmacy, 24/254=9.4%)

32. Chih-Chuang Liaw,* Pei-Chin Chen, Chao-Jen Shih, Sung-Pin Tseng, Ying-Mi Lai, Chi-Hsin Hsu, Pieter C. Dorrestein, and Yu-Liang Yang,* “Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI06 using mass-spectrometry-based metabolomics approach”, Sci. Rep. 2015, 5, 12856; doi: 10.1038/srep12856. (IF: 5.578, Multidisciplinary Sciences, 5/56=8.9%)

33. Ammad Ahmad Farooqi, Kun-Tzu Li, Sundas Fayyaz, Yung-Ting Chang, Muhammad Ismail, Chih-Chuang Liaw, Shyng-Shiou F. Yuan, Jen-Yang Tang,* Hsueh-Wei Chang,* “Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress”, Tumor Biol. 2015, 36, 5743–5752. (IF: 3.611, Oncology, 68/211=32.2%)

34. Ammad Ahmad Farooqi, Shyh-Jong Wu, Yung-Ting Chang, Jen-Yang Tang, Kun-Tzu Li, Muhammad Ismail, Chih-Chuang Liaw, Ruei-Nian Li,* Hsueh-Wei Chang,* “Activation and inhibition of ATM by phytochemicals: Awakening and sleeping the guardian angel naturally”. Arch. Immunol. Ther. Exp. 2015, 63, 357-366. (IF: 3.176, Immunology, 60/148=40.5%)

35. Yung-Ting Chang, Chiung-Yao Huang, Kun-Tzu Li, Ruei-Nian Li, Chih-Chuang Liaw, Shih-Hsiung Wu, Jing-Ru Liu, Jyh-Horng Sheu, Hsueh-Wei Chang, Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage. Arch. Oral Biol. 2016, 66, 147-154.

36. Mingxun Wang, Jeremy J Carver, Vanessa V Phelan, Laura M Sanchez, Neha Garg, Yao Peng, Don Duy Nguyen, Jeramie Watrous, Clifford A Kapono, Tal Luzzatto-Knaan, Carla Porto, Amina Bouslimani, Alexey V Melnik, Michael J Meehan, Wei-Ting Liu, Max Crüsemann, Paul D Boudreau, Eduardo Esquenazi, Mario Sandoval-Calderón, Roland D Kersten, Laura A Pace, Robert A Quinn, Katherine R Duncan, Cheng-Chih Hsu, Dimitrios J Floros, Ronnie G Gavilan, Karin Kleigrewe, Trent Northen, Rachel J Dutton, Delphine Parrot, Erin E Carlson, Bertrand Aigle, Charlotte F Michelsen, Lars Jelsbak, Christian Sohlenkamp, Pavel Pevzner, Anna Edlund, Jeffrey McLean, Jörn Piel, Brian T Murphy, Lena Gerwick, Chih-Chuang Liaw, Yu-Liang Yang, Hans-Ulrich Humpf, Maria Maansson, Robert A Keyzers, Amy C Sims, Andrew R. Johnson, Ashley M Sidebottom, Brian E Sedio, Andreas Klitgaard, Charles B Larson, Christopher A Boya P., Daniel Torres-Mendoza, David J Gonzalez, Denise B Silva, Lucas M Marques, Daniel P Demarque, Egle Pociute, Ellis C O'Neill, Enora Briand, Eric J. N. Helfrich, Eve A Granatosky, Evgenia Glukhov, Florian Ryffel, Hailey Houson, Hosein Mohimani, Jenan J Kharbush, Yi Zeng, Julia A Vorholt, Kenji L Kurita, Pep Charusanti, Kerry L McPhail, Kristian Fog Nielsen, Lisa Vuong, Maryam Elfeki, Matthew F Traxler, Niclas Engene, Nobuhiro Koyama, Oliver B Vining, Ralph Baric, Ricardo R Silva, Samantha J Mascuch, Sophie Tomasi, Stefan Jenkins, Venkat Macherla, Thomas Hoffman, Vinayak Agarwal, Philip G Williams, Jingqui Dai, Ram Neupane, Joshua Gurr, Andrés M. C. Rodríguez, Anne Lamsa, Chen Zhang, Kathleen Dorrestein, Brendan M Duggan, Jehad Almaliti, Pierre-Marie Allard, Prasad Phapale, Louis-Felix Nothias, Theodore Alexandrov, Marc Litaudon, Jean-Luc Wolfender, Jennifer E Kyle, Thomas O Metz, Tyler Peryea, Dac-Trung Nguyen, Danielle VanLeer, Paul Shinn, Ajit Jadhav, Rolf Müller, Katrina M Waters, Wenyuan Shi, Xueting Liu, Lixin Zhang, Rob Knight, Paul R Jensen, Bernhard O Palsson, Kit Pogliano, Roger G Linington, Marcelino Gutiérrez, Norberto P Lopes, William H Gerwick, Bradley S Moore, Pieter C Dorrestein, Nuno Bandeira. ‘Sharing and community curation of mass spectra by GNPS’, Nat. Biotechnol. 2016 34, 828-837.

37. Chun-Kuang Lin, Yu-Ting Wang, Er-Mao Hung, Yu-Liang Yang, Jin-Ching Lee, Jyh-horng Sheu, Chih-Chuang Liaw,* “Butyrolactones and Diketopiperazines from Marine Microbes: Inhibition Effects on Dengue Virus Type 2 Replication”, Planta Med. 2017, 83, 158-163.

38. Fang-Rong Chang, Shih-Ting Huang, Chih-Chuang Liaw, Ming-Hong Yen, Tsong-Long Hwang, Ching-Yeu Chen, Ming-Feng Hou, Shyng-Shiou Yuan, Yuan-Bin Cheng,* Yang-Chang Wu,* “Diterpenes from Grangea maderaspatana”, Phytochemistry 2016, 131, 124-129.

Book Chapter

1.   Chih-Chuang Liaw, Jing-Ru Liou, Tong-Ying Wu, Fang-Rong Chang, Yang-Chang Wu.* Acetogenins from Annonaceae. In Prog. Chem. Org. Nat. Prod. A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Series Title: Progress in the Chemistry of Organic Natural Products; Springer International Publishing: Switzerland; 2016, 101, 113-230. doi: 10.1007/978-3-319-22692-7.

B、研討會論文(2008 to now)

1.  Yung-Yi Cheng, Chih-Chuang Liaw*, Sheng-Chih Chen, 2008, ‘Five New Clerodane Diterpenoids from the Unripe Fruit of Polyalthia longifolia var. pendula’, 2008 PST Medicinal Chemistry Symposium, Apr 25-27, Si-Tou, Taiwan.

2.  Pei-Ru Huang, Chih-Chuang Liaw*, Sheng-Chih Chen, 2008, ‘Studies on the Constituents of Houttuynia Cordata Thunb’, Symposium for the Frontier of Asia-Pacific Pharmaceutical Sciences, May 3-4, Taichung, Taiwan.

3.  Yaun-Chao Huang, Tsong-Long Hwang, Chih-Shiang Chang, Sheng-Chih Chen, Chih-Chuang Liaw*, 2008, ‘Chemical Constituents from the Rhizomes of Helminthostachys zeylanica’, 6th International Symposium for Chinese Medicinal Chemists, July 28-Aug 2, Shanghai, China.

4.  Chih-Chuang Liaw*, Wen-Ying Liao, Shu-Chuan Jao, Chia-Ning Shen, Yang-Chang Wu, Shih-Hsiung Wu, 2008, ‘The Chelating Complex Formation of Acetogenins and Calcium Ion: Implication as Ionophores Relevant to the Biological Function’, 6th International Symposium for Chinese Medicinal Chemists, July 28-Aug 2, Shanghai, China.

5. Wen-Ying Liao, Chih-Chuang Liaw, Sheng-Chih Chen, Chia-Ning Shen, 2008, ‘Nestin-positive stem/progenitor cells derived from pancreatic neoplastic transformation’, Keystone symposia on Stem Cells, Cancer and Aging, Sep 29-Oct 4, Swissotel The Stamford/Biopolis, Singapore.

6. Wen-Ying Liao, Chih-Chuang Liaw, Sheng-Chih Chen, Chia-Ning Shen, 2008, ‘Identification of CD24(+)ABCG2(+) cancer stem/initiating cells from pancreatic ductal adenocarcinoma’, International Symposia on Stem Cells, Epigenetics and Development, Sep 27-28, NTUH International Convention Center, Taipei City, Taiwan.

7. Yung-Yi Cheng, Chia-Hua Liang, Sheng-Chih Chen, and Chih-Chuang Liaw*, 2008, ‘Determination of major active compounds in Carthamus tinctorius L. by LC-NMR’, 97年度台灣藥學會與台灣臨床藥學會聯合年會, Nov. 22, National Defense Medical Center, Taipei City, Taiwan

8. Chia-Hua Liang, Chih-Chuang Liaw, Tzung-Han Chou, Chau-Chen Yang, Hui-Chung Lee, and Guey-Hong Wang, 2008, ‘A novel Cytotoxic Biscembranoid from the formosan Soft Coral Sarcophyton tenuispiculatum’, 2008 Annual Meeting Chemical Society of ROC, Dec 5-7, Changhau, Taiwan.

9.  Yaun-Chao Huang, Tsong-Long Hwang, Mei-Hua Hsu, Sheng-Chih Chen, and Chih-Chuang Liaw*, 2009, ‘Acetogenin and Isoprenylated Flavonoids from Helminthostachys zeylanica with Inhibitory Activity on Superoxide Generation and Elastase Release by Neutrophils’, The 24^th Symposium on Natural Products and Taiwan & 2^nd Forum of the Mainland, Hongkong, Macau, and Taiwan on Natural Products and Medicinal Chemistry & the 10th Anniversary Memorial for the Former President Hsien-Chen Hsieh, May 2-3, Kaohsiung, Taiwan.

10. Chih-Chuang Liaw*, Yaun-Chao Huang, Tsong-Long Hwang, Chih-Shiang Chang, Yu-Liang Yang, Chia-Ning Shen, Wen-Ying Liao, and Sheng-Chih Chen, 2009, ‘Anti-inflammatory Components from the Rhizomes of Helminthostachys zeylanica (L) Hook’, the 50^th Annual Meeting of the American Society of Pharmacognosy, June 27-July 1, Honolulu, Hawaii, USA.

11. Wen-Ying Liao, Zi-Ping Lin, Hui-Chang Lin*, Yu-Ching Lin, Shu-Chuan Jao, Chia-Ning Shen, and Chih-Chuang Liaw*, 2009, ‘Synthesis and Biological Evaluation of N,N’-Ethylen-Bis(2-Hydroxydodecylamine)’, 2009 PST Medicinal Chemistry Symposium, June 28-30, Si-Tou, Taiwan.

12. Jing-Wei Chen, Long-Chi Wang, Yu-Ming Ju, Chih-Chuang Liaw*, 2010, ‘Studies on the Chemical Constituent of Xylaria bambusicola’, 7th International Symposium for Chinese Medicinal Chemists, Feb 1- 5, Kaohsiung, Taiwan.

13.  Yung-Yi Cheng, Tzong-Der Wey, Sheng-Chu Kuo, Sheng-Chih Chen, Chih-Chuang Liaw*, 2010, ‘New Clerodane Diterpenes Increase the Viability of SK-N-MC Human Neuroblastoma Cells under b-amyloid-induced Neurotoxicity’, 7th International Symposium for Chinese Medicinal Chemists, Feb 1- 5, Kaohsiung, Taiwan.

14. Chih-Chuang Liaw,* Yung-Yi Cheng, Yu-Liang Yang, Shih-Hao Wang, Tzong-Der Wei, Sheng-Chu Kuo, and Shih-Hsiung Wu, 2010, ‘New Diterpenes From Polyalthia longifolia var. pendula Protect Sk-N-MC Human Neuroblastoma Cells From -amyloid Insult’, the 51th Annual Meeting of the American Society of Pharmacognosy, July 10-July 14, St. Petersburg, Florida, USA.

15. Shih-Yun Chung, Chih-Chuang Liaw,* Hui-kang Liu, 2010, ‘Studies on the constituent of the dry stem of Tinospora crispa’, The 25th Symposium on Natural Products, Nov. 6-7, Museum of Marine Biology and Aquariums, Pingtung, Taiwan.

16. Shih-Yun Chung, Jin-Bin Wu, Sheng-Chu Kuo, Chih-Chuang Liaw,* 2011, ‘Four new cis-clerodane-type furanoditerpenoids of the dry stem of Tinospora crispa’, 2011 Taiwanese-Russian Organic, Medicinal and Bio Chemistry Interactions (TROMBCI) & PST Medicinal Chemistry Symposium, April 3-6, Citou, Taiwan.

17. Chih-Chuang Liaw,* Shih-Yuan Chung, Shang-Chu Kuo, and Hei-Kang Liu, 2011, ‘cis-Clerodane-Type Furanoditerpenoids from Tinospora crispa Attenuate Beta-Cell Dysfunction Induced by Dexamethasone’, the 52th Annual Meeting of the American Society of Pharmacognosy, July 30-Aug 3, San Diego, California, USA.

18. Hui-Yu Fang, Chih-Chuang Liaw, Shu-Fen Chiou, Zhi-Horng Wen, Yang-Chang Wu, Chi-Hsin Hsu, Wei-Lung Wang, Jyh-Horng Sheu, 2011, ‘Bioactive Brominated Indoles from the Alga Laurencia brongniartii’, the 3rd International Symposium for Marine Biology and Biotechnology, Sep. 21-23, Museum of Marine Biology and Aquariums, Pingtung, Taiwan.

19. Chih-Chuang Liaw,* Wen-Ying Liao, Chien-Sheng Chen, Shu-Chuan Jao, Yang-Chang Wu, Chia-Ning Shen,* and Shih-Hsiung Wu,* 2011, ‘Calcium-Chelating Capability of Tetrahydrofuranic Moieties Modulates the Cytotoxicity of Annonaceous Acetogenins’, The 26th Symposium on Natural Products, Oct. 29-30, China Medical University, Taichung, Taiwan.

20. Wen-Ying Liao, Chia-Ning Shen, Li-Hua Lin, Yu-Liang Yang,Hsin-Ying Han, Jing-Wei Chen, Sheng-Chu Kuo,* Shih-Hsiung Wu,* and Chih-Chuang Liaw,* 2012, ‘Asperjinone, A Nor-Neolignan, and Terrein, A Suppressor of ABCG2-expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus’, 2012 TPST Medicinal Chemistry Symposium, May 5-7, Citou, Taiwan.

21. Pei-Jing Chen, Chih-Chuang Liaw,* Chi-Hsin Hsu, 2012, ‘Studies on the Antibacterial Chemical Constituents of Vibrio sp. (QWI06)’, 2012- Symposium on Natural Products Chemistry for Graduate Students, May 17-18, Museum of Marine Biology and Aquariums, Pingtung, Taiwan.

22. Wen-Ying Liao, Chia-Ning Shen, Li-Hua Lin, Yu-Liang Yang,Hsin-Ying Han, Jing-Wei Chen, Sheng-Chu Kuo,* Shih-Hsiung Wu,* and Chih-Chuang Liaw,* 2012, ‘Asperjinone, A Nor-Neolignan, and Terrein, A Suppressor of ABCG2-expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus’, International Congress on Natural Products Research, July 28-Aug. 1, New York, USA.

23. Chih-Chuang Liaw,* Hui-Kang, Liu, Jia-Ling Chang, Shih-Yuan Chung, and Shang-Chu Kuo, 2012, “Attenuation of Dexamethasone Mediated G1 Phase Arrest in Insulin Secreting Cells by Furanoditerpenoids from Tinospora crispa”. 9th IUPAC International Symposium on Biomolecular Chemistry & 8th International Symposium for Chinese Medicinal Chemists. Aug. 25-29, Beijing, China.

24. Kai-Hsun Chen, Chih-Chuang Liaw,* 2012, ‘New Triterpene Glycosides from the Aerial Root of Avicennia marina’, The 27th Symposium on Natural Products, Oct. 5-7, Kaohsiung Medical University, Kaohsiung, Taiwan.

25. Pei-Jing Chen, Yu-Liang Yang, Chi-Hsin Hsu, Chih-Chuang Liaw,* 2013, ‘Studies on the Antimicrobial Chemical Constituents of Vibrio proteolyticus (Strain QWI06)’, 2013 TPST Medicinal Chemistry Symposium, Jan. 22-24, Pingtung, Taiwan.

26. Chih-Chuang Liaw,* Pei-Jing Chen, Yu-Liang Yang, Chi-Hsin Hsu, 2013, ‘Novel Tyrosin-lipid Derivatives, Vitroprocines, from Marine Bacteria, Vibrio proteolyticus, Exhibited Significant Anti-microbial Activity against Opportunistic Pathogen, Acinetobacter baumannii’, 2013 Gordon Research Conferences: Marine Molecular Ecology, Aug. 11-16, Hongkong, China.

27. Er-Mau Hong, Chih-Chuang Liaw,* 2013, ‘Exploring the Bioactive Components from Marine Bacterium, Microbulbifer variabilis C-03, Which Symbiosis with Palythoa sp.’ The 28th Symposium on Natural Products, Oct. 19-20, National Research institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan.

28. Yu-Ting Wang, Chih-Chuang Liaw,* 2013, ‘Anti-microbial Components from Marine-derived Streptomyces spp. Against Candida albicansis’ The 28th Symposium on Natural Products, Oct. 19-20, National Research institute of Chinese Medicine, Ministry of Health and Welfare, Taipei, Taiwan.

29. Chih-Chuang Liaw,* Yu-Ting Wang, Er-Moa-Hong, 2014, ‘Using Molecular Networking as A new Strategy of Bioactive Natural Products Discovery from Marine Microbes’, 2014 PST Medicinal Chemistry Symposium, Jan. 21-23, National Dong Hwa University, Hua-lien, Taiwan.

30. Yu-Ting Wang, Ya-Ping Jhang, Chih-Chuang Liaw,* 2014, ‘Anti-microbial Components from Marine-derived Streptomyces spp. Against Candida albicansis’, The 3rd Asia-Pacific Coral Reef Symposium, June 23-27, Howard Hotel, Pingtung, Taiwan.

31. Er-Mao Hung, Ya-Ping Jhang, Chih-Chuang Liaw,* 2014, ‘Studies on the Chemical Constituents of the Marine Microbe Microbulbifer variabilis and their Biological Activities, The 3rd Asia-Pacific Coral Reef Symposium, June 23-27, Howard Hotel, Pingtung, Taiwan.

32. Yi-yu, Chen, Ya-Ping Jhang, Chih-Chuang Liaw,* 2014, ‘The investigation of Antimicrobial components of Marine-derived Fungi, Trichodrrma spp. by LC-MS/MS Molecular Networking Analysis’, The 3rd Asia-Pacific Coral Reef Symposium, June 23-27, Howard Hotel, Pingtung, Taiwan.

33. Po-Yi Cheng, Ya-Ping Jhang, Ka-Lai Pang, Chih-Chuang Liaw,* 2014, ‘Study in the Antibacterial Components from Palythoa-Symbiotic Fungus, Fusarium solani’, The 3rd Asia-Pacific Coral Reef Symposium, June 23-27, Howard Hotel, Pingtung, Taiwan.

34. Chih-Chuang Liaw,* 2014, ‘Study in the Antibacterial Components from Palythoa-Symbiotic Fungus, Fusarium solani’, The 10th International Mycological Congress (IMC10), August 3-8, Queen Sirikit National Convention Center, Bangkok, Thailand.

35. Yi-yu Chen, Ya-Ping Jhang, Chih-Chuang Liaw,* 2014, ‘The investigation of Antimicrobial components of Marine-derived Fungi, Trichodrrma spp. by LC-MS/MS Molecular Networking Analysis’, The 29th Symposium on Natural Products, Sep. 27-28, Kaohsiung Medical University, Kaohsiung, Taiwan.

36. Po-Yi Cheng, Ya-Ping Jhang, Ka-Lai Pang, Chih-Chuang Liaw,* 2014, ‘The Antibacterial Components from Palythoa-Symbiotic Fungus, Fusarium solani FS-01’, 2014 Annual Meeting of Chinese Chemistry Society, Nov. 21-22, Industrial Technology Research Institute, Hsinchu, Taiwan.

37. Yi-Yu Chen, Yu-Liang Yang, Chih-Chuang Liaw,* 2015, “The Investigation on the Siderophore-like Organic Molecules from Marine-derived Fungi, Trichodrrma spp. by LC-MS/MS Molecular Networking Analysis”, 2015 MOST Ocean Sciences Conference, The Garden Villa, April 30th-May 1st, Kaohsiung, Taiwan.

38. Mo Aqib Raza Khan, Chih-Chaung Liaw,* 2015, “The Investigation on Siderophore-like Organic Ligands from Marine-derived Fungus Aspergillus sp.”, 2015 MOST Ocean Sciences Conference, The Garden Villa, April 30th-May 1st, Kaohsiung, Taiwan.

39. Yan-Ching Hsu, Wen-Tseng Lo, Chih-Chuang Liaw,* 2015, “Searching the biomarkers of metaproteomics of zooplanktons for their qualification and quantification using LC-MS/MS”, 2015 MOST Ocean Sciences Conference, The Garden Villa, April 30th-May 1st, Kaohsiung, Taiwan.

40. Po-Yi Cheng, Ya-Ping Jhang, Ka-Lai Pang, Chih-Chuang Liaw,* 2015, “The Investigation on the Marine Ligands from A Marine-Derived Fungus, Aspergillus sp. strain K16-16-21”, 2015 MOST Ocean Sciences Conference, The Garden Villa, April 30th-May 1st, Kaohsiung, Taiwan.

41. Yi-Yu Chen, Chih-Chuang Liaw,* 2015, “Bioactive Polypeptides from Marine-derived Fungi, Trichodrrma spp. by LC-MS/MS and Molecular Networking Analysis”, 63rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA2015), August 23 – 27, Budapest, Hungary.

42. Mo Aqib Raza Khan, Chih-Chuang Liaw,* 2015, “Investigation on Anti-microbial Organic Compounds from Marine-derived Fungus Aspergillus terreus”, The 30th Symposium on Natural Products, Sep. 18-19, Taipei Medical University, Taipei, Taiwan.

C. 口頭報告

1.  Chih-Chuang Liaw, 2009, “Recent Research on the Bioactive compounds of Helminthostachys zeylanica”, 2010年兩岸林產特產物研討會, Jan. 25-29, 惠蓀林場, 南投, 台灣.

4.  Chih-Chuang Liaw, 2010, “From FID to Structure - Case Learning from Natural Products”, 2010 Annual Meeting of Chinese Chemistry Society, Dec. 4-5, Taipei, Taiwan

3. Chih-Chuang Liaw, 2011, “The Historic Perspective of Pharmaceutical Industry”, Department of Bioscience Technology, Chung Yuan Christian University, Mar. 1st, Chung Li, Taiwan.

4. Chih-Chuang Liaw, 2012, “The rapid isolation and structural elucidation of bioactive secondary metabolites from marine microorganisms”, 第18屆分析技術交流研討會, 國立中山大學, May 26th-27th, 高雄, 台灣.

5. Chih-Chuang Liaw, 2012, “The diversity and biofunctions of secondary metabolites from extreme microbe”, 第27屆天然藥物研討會, 高雄醫學大學, Oct. 5th-7th, 高雄, 台灣.

6. Chih-Chuang Liaw, 2013, “The Medicinal Application of Marine Natural Products”, March 6, National Chia-Yi University, Chia-Yi County, Taiwan.

7. Chih-Chuang Liaw, 2014, “The Study on the Marine Ligands Produced by Marine Microbes from Offshore Southern Taiwan”, 2014 MOST Ocean Sciences Conference, Howard Civil Service international House, April 27th-May 1st, Taipei, Taiwan.

8. Chih-Chuang Liaw, 2014, “Mining Marine Microbes for Discovering Novel Anti-bacterial Marine Natural Products by Molecular Networking”, the 10th Asia-Pacific Marine Biotechnology Conference, Academia Sinica, May. 4th-8th, Taipei, Taiwan.

9. Chih-Chuang Liaw, 2014, “Bioactive Compounds from Marine Microbes by Molecular Networking”, 2014 the 29th Symposium on Natural Products, Kaohsiung Medical University, Sep. 27th-28th, Kaohsiung City, Taiwan.

10. Chih-Chuang Liaw, 2014, “Recent Progress in Bioactive Natural Products from Marine Microbes”, Inviting Talk in Department of Chemistry, National Chung-Hsing University, Oct 15th, Taichung, Taiwan.

11. Chih-Chuang Liaw, 2014, “Antimicrobial Natural Products from Marine Microbes Targeted by Modern Mass Technologies”, 28th International Symposium on the Chemistry of Natural Products and 8th International Conference on Biodiversity (ISCNP28), Parkyard Hotel, Oct. 19th- 24th, Shanghai, China.

12. Chih-Chuang Liaw, 2015, “The Researches and Development of Biofunctional Secondary Metabolites from Marine Microorganisms”, Inviting Talk in Department of Plant Pathology, National Chung-Hsing University, Jan. 8th, Taichung, Taiwan.

13. Chih-Chuang Liaw, 2015, “The Investigation on Secondary Metabolites from Marine Microorganisms as Marine Organic Ligands to Complex Trace Metals”, 2015 MOST Ocean Sciences Conference, The Garden Villa, April 30th-May 1st, Kaohsiung, Taiwan.

14. Chih-Chuang Liaw, 2016, “The Role of Metal Ions in the Biofunctional Natural Products”, the 4th Asian Chemical Biology Conference, 85 Sky Tower Hotel, Nov. 28th-Dec. 1st, Kaohsiung, Taiwan.

15. Chih-Chuang Liaw, 2016, “Discovery of New Antimicrobial Natural Products from Marine Microbes by Mass Spectrometry Technology”, 2016 Annual Meeting of Chemical Society, Dec. 3rd-4th, Taichung, Taiwan.