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Chih-Chuang Liaw, Ph. D.
Professor
Highest Education: Graduate Institute of
Pharmacy, KMU
Major: Natural Products Chemistry
Location: MRB4003
Tel: +886-7-5252000#5058
Fax: +886-7-5255020
E-mail:
ccliaw@mail.nsysu.edu.tw
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2017 Service and Learning
Practice of Marine Resources
Please remind the
Note
Finding Jobs
1. Research assistants for natural products isolation.
Contact me!
2. Undergraduate students for
extraction, identification of secondary metabolites from marine organisms,
herbs and medicinal plants.
Contact me.
Group meeting schedule
Group meeting will take place bi-weekly on
Thursday in this semester.
Recent publications
1. Chih-Chuang Liaw,* Yu-Liang Yang, Chun-Kuang
Lin, Jin-Ching Lee, Wen-Ying Liao, Chia-Ning Shen, Jyh-Horng Sheu, and Shih-Hsiung
Wu,* “New Meroterpenoids from Aspergillus terreus with Inhibition of
Cyclooxygenase-2 Expression”, Org. Lett. 2015, 17, 2330–2333. (IF: 6.364,
Chemistry, Organic, 4/57=7.0%)
2. Chun-Kuang Lin, Chin-Kai Tseng, Kai-Hsun
Chen, Shih-Hsiung Wu, Chih-Chuang Liaw,* Jin-Ching Lee,* “Betulinic acid
exerts anti-hepatitis C virus activity via the suppression of NF-κB and
MAPK-ERK1/2-mediated cyclooxygenase-2 expression”, Br. J. Pharmacol. 2015,
172, 4481-4492. (IF: 4.842, Pharmacology & Pharmacy, 24/254=9.4%)
3. Chih-Chuang Liaw,* Pei-Chin Chen, Chao-Jen
Shih, Sung-Pin Tseng, Ying-Mi Lai, Chi-Hsin Hsu, Pieter C. Dorrestein, and
Yu-Liang Yang,* “Vitroprocines, new antibiotics against Acinetobacter
baumannii, discovered from marine Vibrio sp. QWI06 using
mass-spectrometry-based metabolomics approach”, Sci. Rep. 2015, 5, 12856;
doi: 10.1038/srep12856. (IF: 5.578, Multidisciplinary Sciences, 5/56=8.9%)
4. Ammad Ahmad Farooqi, Kun-Tzu Li, Sundas
Fayyaz, Yung-Ting Chang, Muhammad Ismail, Chih-Chuang Liaw, Shyng-Shiou F.
Yuan, Jen-Yang Tang,* Hsueh-Wei Chang,* “Anticancer drugs for the modulation
of endoplasmic reticulum stress and oxidative stress”, Tumor Biol. 2015, 36,
5743–5752. (IF: 3.611, Oncology, 68/211=32.2%)
5. Ammad Ahmad Farooqi, Shyh-Jong Wu,
Yung-Ting Chang, Jen-Yang Tang, Kun-Tzu Li, Muhammad Ismail, Chih-Chuang
Liaw, Ruei-Nian Li,* Hsueh-Wei Chang,* “Activation and inhibition of ATM by
phytochemicals: Awakening and sleeping the guardian angel naturally”. Arch.
Immunol. Ther. Exp. 2015, 63, 357-366. (IF: 3.176, Immunology, 60/148=40.5%)
6. Yung-Ting Chang, Chiung-Yao Huang, Kun-Tzu
Li, Ruei-Nian Li, Chih-Chuang Liaw, Shih-Hsiung Wu, Jing-Ru Liu, Jyh-Horng
Sheu, Hsueh-Wei Chang, Sinuleptolide inhibits proliferation of oral cancer
Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage. Arch.
Oral Biol. 2016, 66, 147-154.
7. Mingxun Wang, Jeremy J Carver, Vanessa V
Phelan, Laura M Sanchez, Neha Garg, Yao Peng, Don Duy Nguyen, Jeramie
Watrous, Clifford A Kapono, Tal Luzzatto-Knaan, Carla Porto, Amina
Bouslimani, Alexey V Melnik, Michael J Meehan, Wei-Ting Liu, Max Crüsemann,
Paul D Boudreau, Eduardo Esquenazi, Mario Sandoval-Calderón, Roland D
Kersten, Laura A Pace, Robert A Quinn, Katherine R Duncan, Cheng-Chih Hsu,
Dimitrios J Floros, Ronnie G Gavilan, Karin Kleigrewe, Trent Northen, Rachel
J Dutton, Delphine Parrot, Erin E Carlson, Bertrand Aigle, Charlotte F
Michelsen, Lars Jelsbak, Christian Sohlenkamp, Pavel Pevzner, Anna Edlund,
Jeffrey McLean, Jörn Piel, Brian T Murphy, Lena Gerwick, Chih-Chuang Liaw,
Yu-Liang Yang, Hans-Ulrich Humpf, Maria Maansson, Robert A Keyzers, Amy C
Sims, Andrew R. Johnson, Ashley M Sidebottom, Brian E Sedio, Andreas
Klitgaard, Charles B Larson, Christopher A Boya P., Daniel Torres-Mendoza,
David J Gonzalez, Denise B Silva, Lucas M Marques, Daniel P Demarque, Egle
Pociute, Ellis C O'Neill, Enora Briand, Eric J. N. Helfrich, Eve A
Granatosky, Evgenia Glukhov, Florian Ryffel, Hailey Houson, Hosein Mohimani,
Jenan J Kharbush, Yi Zeng, Julia A Vorholt, Kenji L Kurita, Pep Charusanti,
Kerry L McPhail, Kristian Fog Nielsen, Lisa Vuong, Maryam Elfeki, Matthew F
Traxler, Niclas Engene, Nobuhiro Koyama, Oliver B Vining, Ralph Baric,
Ricardo R Silva, Samantha J Mascuch, Sophie Tomasi, Stefan Jenkins, Venkat
Macherla, Thomas Hoffman, Vinayak Agarwal, Philip G Williams, Jingqui Dai,
Ram Neupane, Joshua Gurr, Andrés M. C. Rodríguez, Anne Lamsa, Chen Zhang,
Kathleen Dorrestein, Brendan M Duggan, Jehad Almaliti, Pierre-Marie Allard,
Prasad Phapale, Louis-Felix Nothias, Theodore Alexandrov, Marc Litaudon,
Jean-Luc Wolfender, Jennifer E Kyle, Thomas O Metz, Tyler Peryea, Dac-Trung
Nguyen, Danielle VanLeer, Paul Shinn, Ajit Jadhav, Rolf Müller, Katrina M
Waters, Wenyuan Shi, Xueting Liu, Lixin Zhang, Rob Knight, Paul R Jensen,
Bernhard O Palsson, Kit Pogliano, Roger G Linington, Marcelino Gutiérrez,
Norberto P Lopes, William H Gerwick, Bradley S Moore, Pieter C Dorrestein,
Nuno Bandeira. ‘Sharing and community curation of mass spectra by GNPS’,
Nat. Biotechnol. 2016 34, 828-837.
8. Fang-Rong Chang, Shih-Ting Huang, Chih-Chuang
Liaw, Ming-Hong Yen, Tsong-Long Hwang, Ching-Yeu Chen, Ming-Feng Hou,
Shyng-Shiou Yuan, Yuan-Bin Cheng,* Yang-Chang Wu,* “Diterpenes from Grangea
maderaspatana”, Phytochemistry 2016, 131, 124-129.
9. Chun-Kuang Lin, Yu-Ting Wang, Er-Mao Hung,
Yu-Liang Yang, Jin-Ching Lee, Jyh-horng Sheu, Chih-Chuang Liaw,*
“Butyrolactones and Diketopiperazines from Marine Microbes: Inhibition
Effects on Dengue Virus Type 2 Replication”, Planta Med. 2017, 83, 158-163.
Book
Chapter
1. Chih-Chuang
Liaw, Jing-Ru Liou, Tong-Ying Wu, Fang-Rong
Chang, Yang-Chang Wu.* Acetogenins from Annonaceae. In
Prog. Chem. Org. Nat. Prod.
A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Jun'ichi Kobayashi, Series
Title: Progress in the Chemistry of Organic Natural Products; Springer
International Publishing: Switzerland;
2016, 101, 113-230.
doi: 10.1007/978-3-319-22692-7.
Honors:
1. 2004 Outstanding Graduate Student Award, Kaohsiung
Medical University
2. 2008 Poster Presentation Award, The 6th
International Symposium for Chinese Medicinal Chemists (ISCMC)
3. 2015 NSYSU-KMU Joint Outstanding Research Award,
National Sun Yat-sen University
4. 2016 NSYSU Excellent Research Teacher Award,
National Sun Yat-sen University
5. 2016 NSYSU Excellent Teaching Award, National Sun
Yat-sen University
6. 2017 NSYSU Excellent Research Teacher Award,
National Sun Yat-sen University
Highlight:
The Chemicobiological
Study of Marine Microbial Secondary Metabolites in Medicine and Ecology
Natural Products on the
Treatment
of Alzheimer's Disease.
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